Vivekanandan Ramalingam

Jun 6, 2024 | biorxiv.org | Georgi K. Marinov |Vivekanandan Ramalingam |William J. Greenleaf |Anshul Kundaje

AbstractIn most eukaryotes, mitochondrial organelles contain their own genome, usually circular, which is the remnant of the genome of the ancestral bacterial endosymbiont that gave rise to modern mitochondria. Mitochondrial genomes are dramatically reduced in their gene content due to the process of endosymbiotic gene transfer to the nucleus; as a result most mitochondrial proteins are encoded in the nucleus and imported into mitochondria.