W. Nathaniel Brennen

Oct 31, 2023 | nature.com | Joakin O Mori |W. Nathaniel Brennen |Mindy K Graham |Tamara L. Lotan |Srinivasan Yegnasubramanian |William Nelson | +2 more

AbstractThe stromal component of the tumour microenvironment in primary and metastatic prostate cancer can influence and promote disease progression. Within the prostatic stroma, fibroblasts are one of the most prevalent cell types associated with precancerous and cancerous lesions; they have a vital role in the structural composition, organization and integrity of the extracellular matrix.