W Smithfield

Featured in: Favicon

Articles

High Density Isochronal Repolarisation Mapping (iREM) and Reentry Vulnerability Estimation for Scar-related VT Ablation: Mechanistic Basis, Clinical Application and Challenges

Oct 30, 2024 | academic.oup.com | W Smithfield

Alterations in repolarisation gradients and increased heterogeneity are key electrophysiological determinants of ventricular arrhythmogenesis across a variety of aetiologies with and without structural heart disease. High-density repolarisation mapping to localise these repolarisation abnormalities could improve characterisation of the individual arrhythmogenic substrate and inform more targeted ablation.
Simultaneous focal boost with stereotactic radiotherapy for localised intermediate to high-risk prostate cancer: Primary outcomes of the SPARC phase II trial

Mar 15, 2024 | redjournal.org | W Smithfield |Luke Nicholls |Raymond Terrace |Daniel Henderson

Abstract : Dose escalated radiotherapy is associated with better biochemical control at the expense of toxicity. Stereotactic body radiotherapy (SBRT) with dose escalation to the dominant intraprostatic lesion (DIL) provides a logical approach to improve outcomes in high-risk disease whilst limiting toxicity. This study evaluated the toxicity and quality of life (QOL) with CyberKnife-based SBRT and simultaneous integrated boost in localised prostate cancer.

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.