Wang-Jing Mu

3 weeks ago | nature.com | Jie-Ying Zhu |Min Chen |Wang-Jing Mu |Hong-Yang Luo |Shan Li |Lin-Jing Yan | +4 more

AbstractExercise combats obesity and metabolic disorders, but the underlying mechanism is incompletely understood. KLF10, a transcription factor involved in various biological processes, has an undefined role in adipose tissue and obesity. Here, we show that exercise facilitates adipocyte-derived KLF10 expression via SIRT1/FOXO1 pathway.