Weiwen Liang

Apr 22, 2024 | biorxiv.org | Huibin Lv |Qi Wen Teo |Chang-Chun D. Lee |Weiwen Liang

AbstractUnderstanding how immune history influences influenza immunity is essential for developing effective vaccines and therapeutic strategies. This study investigates the antigenic imprinting of influenza hemagglutinin (HA) and neuraminidase (NA) using a mouse model with sequential infection by four seasonal H1N1 strains.

Jan 8, 2024 | biorxiv.org | Jingzhi Lou |Weiwen Liang |Lirong Cao |Shi Zhao

AbstractA predictive evolutionary model was developed to forecast representative influenza viral strains and select vaccine strains for upcoming epidemic seasons. Influenza virus continuously evolves to escape human adaptive immunity and generates seasonal epidemics.

Aug 24, 2023 | biorxiv.org | Jingzhi Lou |Weiwen Liang |Lirong Cao |Shi Zhao

AbstractA predictive evolutionary model was developed to forecast representative influenza viral strains for upcoming epidemic seasons. Influenza virus continuously evolves to escape human adaptive immunity and generates seasonal epidemics.