Wen-Hsien Hou

Aug 5, 2024 | cell.com | Wen-Hsien Hou |Meet Jariwala |Kai-Yi Wang |Anna Seewald |Yu-Ling Lin |Alessia Ricci | +4 more

Highlights•Auditory fear conditioning triggers inhibitory synaptic plasticity in CeL neurons•An inhibitory engram, mainly composed of SST(+) neurons, is identified in the CeL•CeL inhibitory engrams participate in the encoding specificity of conditioned fear•Inhibiting CeL engrams enhances fear expressionSummaryEngrams, which are cellular substrates of memory traces, have been identified in various brain areas, including the amygdala.