Wenling Liu

Mar 25, 2024 | onlinelibrary.wiley.com | Wenling Liu |Mingming Zhu |Yaming Xi

1 INTRODUCTION Acute myeloid leukaemia (AML) is a phenotypically highly heterogeneous hematologic malignancy characterised by abnormal clonal expansion and stalled differentiation of haematopoietic stem cells.1, 2 AML primarily manifests as the aberrant proliferation of primitive or naive myeloid cells in peripheral blood and bone marrow (BM).3 The predominant treatment strategies for AML include induction-remission chemotherapy and intensive therapy after remission; however, the overall...