William J Dreyer

1 month ago | digitalcommons.library.tmc.edu | Erica Lay |Mahshid Azamian |Susan W. Denfield |William J Dreyer

KeywordsActin Cytoskeleton, Animals, Cardiomyopathies, Cardiomyopathy, Dilated, Cytoskeletal Proteins, Heart, Humans, Infant, Newborn, Mice, Muscle Proteins, Sarcomeres, LMOD2, dilated cardiomyopathy, short thin filament length, autosomal recessive disease, loss of function variantAbstractLeiomodin-2 (LMOD2) is an important regulator of the thin filament length, known to promote elongation of actin through polymerization at pointed ends.