Wolfram Doehner

Dec 1, 2024 | jacc.org | Wolfram Doehner |Stefan Anker |Javed Butler |Faiez Zannad

References1. "Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial)". Am J Cardiol . 2014;114:1713-1721. 2. "Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging". Circulation . 2003;107:1991-1997. 3.

May 10, 2024 | fis.uke.de | Stephan von Haehling |Georg-August-University Göttingen |Wolfram Doehner |Ruben Evertz

BACKGROUND AND AIMS: Evidence is lacking that correcting iron deficiency (ID) has clinically important benefits for patients with heart failure with preserved ejection fraction (HFpEF). METHODS: FAIR-HFpEF was a multicentre, randomized, double-blind trial designed to compare intravenous ferric carboxymaltose (FCM) with placebo (saline) in 200 patients with symptomatic HFpEF and ID (serum ferritin < 100 ng/mL or ferritin 100-299 ng/mL with transferrin saturation < 20%).

Oct 8, 2023 | onlinelibrary.wiley.com | Ralph K Akyea |George Ntaios |Wolfram Doehner

Introduction Metabolic syndrome refers to a cluster of interrelated metabolic abnormalities mostly including generalized obesity, glucose intolerance, arterial hypertension and dyslipidaemia.1 It is estimated that about 20–30% of the adult population in most countries can be classified as having metabolic syndrome.2 The increased risk of cardiovascular disease (CVD) outcomes associated with metabolic syndrome is well established.3 In the healthy population, the presence of excessive body...