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  • Oct 18, 2024 | onlinelibrary.wiley.com | zhiyong Liu |Xiahui Lin |Danying Zhang |Dezhen Guo

    1 Introduction Hepatocellular carcinoma (HCC) is the most common type of liver cancer and remains a health challenge worldwide.[1] The majority of HCC cases usually occur in inflamed liver, inflammatory status, and immune responses in the tumor microenvironment (TME), which can markedly affect the biological behavior of malignancy.[2] Early investigations on immunotherapy have identified that anti-tumor responses modulated by immune cells could serve as effective treatment tools for solid or...

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