Xianquan Zhan

May 9, 2023 | frontiersin.org | Xianquan Zhan |Angelo Finelli |Nicholas Pavlidis

1 IntroductionA combination of interconnected conditions known as the metabolic syndrome (MetS) is thought to significantly raise the risk of type 2 diabetes (T2DM) and cardiovascular disease. Its main components include hypertriglyceridemia, reduced HDL cholesterol concentration, hypertension, insulin resistance, and central obesity (1).