Xiaobo Bao

Jan 11, 2024 | pubs.rsc.org | Xiaobo Bao |Guoli Wang |Xu Dong |Mengxiao Zhu

I2/CF3CO2Ag-mediated iodolactonization of various allenoic acids to access versatile 6- to 9-membered ring vinylic iodolactones Medium-sized lactones are important structural units, but their synthesis remains a great challenge. Herein, we report I2/CF3CO2Ag-mediated iodolactonization of allenoic acids to synthesize various 6- to 9-membered ring vinylic iodolactones in 16~89% yield.