Xiaoguang Lei

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Articles

Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch

Oct 29, 2024 | cell.com | Yu Chen |Yulong Li |Xiaoguang Lei

Keywordscholestatic pruritusbile acidsMRGPRX4cryo-EM structureOCAfarnesoid X receptornon-alcoholic steatohepatitisliver diseases3-sulfonated bile acidsdeoxycholic acidGet full text accessLog in, subscribe or purchase for full access. References1. Younossi, Z.M. ∙ Golabi, P. ∙ de Avila, L. ... The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysisJ. Hepatol. 2019; 71:793-8012. Lazarus, J.V. ∙ Mark, H.E. ∙ Anstee, Q.M. ...
Hunting for the Intermolecular Diels-Alderase

May 27, 2024 | pubs.acs.org | Lei Gao |Qi Ding |Xiaoguang Lei
Hunting for the Intermolecular Diels-Alderase

May 27, 2024 | dx.doi.org | Lei Gao |Qi Ding |Xiaoguang Lei

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