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Xiaohua Peng

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Articles

  • A modified glycosylase base editor without predictable DNA off‐target effects

    Jun 30, 2024 | febs.onlinelibrary.wiley.com | Meng Lian |Tao Chen |Min Chen |Xiaohua Peng

    Supporting Information Filename Description feb214970-sup-0001-Figures.docxWord 2007 document , 8.2 MB Fig. S1. FACS analysis of wild-type (WT) cells and cells transfected with UNG-YE1-nCas9-2A-mCherry or TaC9-GBEYE1 (UNG-nCas9-2A-mCherry and YE1-TALE-2A-EGFP). Fig. S2. Engineering of GBEs. Fig. S3. Engineering of TaC9-GBEYE1 variants with three transactivation modules. Fig. S4. Base editing efficiency of UNG-YE1-nCas9 and TaC9-GBEYE1 on-targets and off-targets.

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