Xing Sheng

2 months ago | nature.com | Liu Wang |Jiaxin Lei |Shirong Wang |Qingyun Wang |Xing Sheng |Yubo Fan | +3 more

AbstractMonitoring the early-stage healing of severe traumatic nerve injuries is essential to gather physiological and pathological information for timely interventions and optimal clinical outcomes. Traditional diagnostic methods relying on physical examinations, imaging tools, and intraoperative electrophysiological testing present great challenges in continuous and remote monitoring.

Aug 19, 2024 | biorxiv.org | Xing Sheng

AbstractAdvanced brain-machine interfaces (BMIs) demand implantable devices that offer flexibility, high-density and high-throughput capabilities. Conventional neural electrodes are constrained by the wiring strategy. Here we present a flexible and implantable electrocorticography (ECoG) device array (NeuroCam) based on metal-oxide semiconductor thin-film transistors (TFTs), to record brain activities at a large scale.

Jun 2, 2024 | nature.com | Xing Sheng |Milin Zhang |Shirong Wang |Yu Wang

AbstractOptoelectronic neural interfaces can leverage the photovoltaic effect to convert light into electrical current, inducing charge redistribution and enabling nerve stimulation. This method offers a non-genetic and remote approach for neuromodulation. Developing biodegradable and efficient optoelectronic neural interfaces is important for achieving transdermal stimulation while minimizing infection risks associated with device retrieval, thereby maximizing therapeutic outcomes.

Mar 1, 2024 | biorxiv.org | Xing Sheng

AbstractThe development of advanced neural modulation techniques is crucial to neuroscience research and neuroengineering applications. Recently, optical-based, non-genetic modulation approaches have been actively investigated to remotely interrogate the nervous system with high precision. Here, we show that a thin-film, silicon (Si)-based diode device is capable to bidirectionally regulate in vitro and in vivo neural activities upon adjusted illumination.

Nov 27, 2023 | dx.doi.org | Chen Hu |Liu Wang |Shangbin Liu |Xing Sheng

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