Xixi Wu

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Integration of Deep Learning and Sub-regional Radiomics Improves the Prediction of Pathological Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients

Jan 13, 2025 | academicradiology.org | Xixi Wu |Jinyong Wang |Chao Chen |Weimin Cai |Yu Guo |Kun Guo | +5 more

Key WordsDeep learningSub-regional radiomicsPathological complete response (pCR)Neoadjuvant chemoradiotherapyLocally advanced rectal cancer (LARC)INTRODUCTIONFor patients with locally advanced rectal cancer (LARC), the standard cancer treatment protocol involves neoadjuvant chemoradiotherapy, followed by total mesorectal excision (TME), and subsequent adjuvant chemotherapy, which is effective in significantly reducing tumor size and downstaging tumor stage (1).

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