Xue-Xin Wei

Apr 22, 2024 | biorxiv.org | Ronan O'Shea |Ian Nauhaus |Xue-Xin Wei |Nicholas J. Priebe

AbstractThe retina maintains sensitivity over a large range of luminance intensities by switching between rod and cone photoreceptors. This luminance adaptation has been shown to alter the receptive fields and interneuronal correlations of retinal ganglion cells (RGCs).

Feb 15, 2024 | nature.com | Michael Hahn |Xue-Xin Wei

AbstractPerceptual biases are widely regarded as offering a window into the neural computations underlying perception. To understand these biases, previous work has proposed a number of conceptually different, and even seemingly contradictory, explanations, including attraction to a Bayesian prior, repulsion from the prior due to efficient coding and central tendency effects on a bounded range. We present a unifying Bayesian theory of biases in perceptual estimation derived from first principles.

May 4, 2023 | nature.com | Alexandra T. Keinath |Xue-Xin Wei

Correction to: Nature https://doi.org/10.1038/s41586-023-05813-2 Published online 22 March 2023 In the version of this article initially published, there was a typographical error in the seventh sentence of the Methods “Surgeries” subsection, where in the text now reading “One week after injection, a 0.5-mm-diameter gradient refractive index (GRIN) relay lens (Go!Foton) was implanted above the ADN (AP, –1.05; ML, 0.8; DV, −3),” the AP coordinate “–1.05” originally read “1.8.” The error has...

Apr 21, 2023 | nature.com | Xue-Xin Wei

AbstractNeural representation is often described by the tuning curves of individual neurons with respect to certain stimulus variables. Despite this tradition, it has become increasingly clear that neural tuning can vary substantially in accordance with a collection of internal and external factors. A challenge we are facing is the lack of appropriate methods to accurately capture the moment-to-moment tuning variability directly from the noisy neural responses.

Mar 22, 2023 | nature.com | Alexandra T. Keinath |Xue-Xin Wei

AbstractThe head direction (HD) system functions as the brain’s internal compass1,2, classically formalized as a one-dimensional ring attractor network3,4. In contrast to a globally consistent magnetic compass, the HD system does not have a universal reference frame. Instead, it anchors to local cues, maintaining a stable offset when cues rotate5,6,7,8 and drifting in the absence of referents5,8,9,10.