Xuhong Qian

Jun 10, 2023 | pubs.acs.org | Cong Zhou |Zhong Li |Xuhong Qian |Jiagao Cheng

The identification of novel pyrazolyl acrylonitrile acaricides with improved properties is of great value for the control of phytophagous mites. A series of innovative silicon-containing pyrazolyl acrylonitriles were rationally designed by applying a bioisosteric carbon–silicon replacement strategy and prepared based on novel synthetic methodology. As a result of our research, we discovered compound A25 which possesses outstanding acaricidal activity.