Y Dodzi Motchon

Mar 27, 2024 | biorxiv.org | Y Dodzi Motchon |Kevin Sack |Mazin S Sirry |N John Nchejane

AbstractPurpose: Biomaterial and stem cell delivery are promising approaches to treating myocardial infarction. However, the mechanical and biochemical mechanisms underlying the observed therapeutic benefits require further clarification. This study aimed to assess the deformation of stem cells injected with the biomaterial into the infarcted heart.

May 12, 2023 | biorxiv.org | Kevin Sack |Y Dodzi Motchon |Mazin S Sirry |N John Nchejane

AbstractBiomaterial and stem cell delivery are promising approaches to treating myocardial infarction. However, the mechanical and biochemical mechanisms underlying the observed therapeutic benefits require further clarification. This computational study aimed to assess deformation and resulting transforming growth factor β (TGF-β) expression of stem cells injected with the biomaterial into the infarcted heart.