Yalin Tu

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Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinoma

Nov 1, 2024 | gut.bmj.com | Yalin Tu |Haoran Wu |Chengpeng Zhong |Yan Liu

DiscussionRecent progress from therapeutic checkpoint inhibition in the clinic has provided new insights into the rate limiting steps of the cancer-immunity cycle.44 One of the key mechanisms that render the immune system unable to control tumour growth is the deficiency in IFNγ signalling.

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