Yamuna Krishnan

Oct 29, 2024 | cell.com | Roni Levin-Konigsberg |Koushambi Mitra |Kaitlyn Spees |Akshat Kumar Nigam |katherine liu |Camille Januel | +6 more

Keywordslysosome metabolismSLC12A9ammoniumion transportlysosome volume regulationchlorideGet full text accessLog in, subscribe or purchase for full access. References1. Walker, V. Chapter Three - . Ammonia Metabolism and Hyperammonemic DisordersElsevier,Makowski, S. in: Advances in Clinical Chemistry. 67. 2014; 73-1502. Spinelli, J.B. ∙ Yoon, H. ∙ Ringel, A.E. ... Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomassScience. 2017; 358:941-9463. Takiguchi, M. ∙ Mori, M.

Mar 28, 2024 | dx.doi.org | Yamuna Krishnan

ConspectusDNA nanodevices are nanoscale assemblies, formed from a collection of synthetic DNA strands, that may perform artificial functions. The pioneering developments of a DNA cube by Nadrian Seeman in 1991 and a DNA nanomachine by Turberfield and Yurke in 2000 spawned an entire generation of DNA nanodevices ranging from minimalist to rococo architectures.

Nov 27, 2023 | nature.com | Koushambi Mitra |Yamuna Krishnan

To determine the physiologically relevant oligomeric form of membrane proteins is extremely challenging. Now an elegant method of counting the oligomers in membrane proteins in near-native states is presented, using photobleaching and nanodiscs formed directly from cellular membranes. Nearly a third of all proteins within a cell are associated with membranes. These proteins perform diverse functions as receptors, transporters, ion channels and enzymes.