Yangyang He

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Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression - Nature Communications

Nov 12, 2024 | nature.com | Yangyang He |Fan Yang |Lin Yang |Haoyang Yuan |Yinghui Chen |Xiulin Wu | +3 more

AbstractCrystalline silica (CS) particle exposure leads to silicosis which is characterized as progressive fibrosis. Fibroblasts are vital effector cells in fibrogenesis. Emerging studies have identified immune sentinel roles for fibroblasts in chronic disease, while their immune-modulatory roles in silicosis remain unclear.

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