Yaxing Wu

2 weeks ago | pubs.acs.org | Yaxing Wu |Xiuling Wang |Zhiyuan Bao |Zhenyu Wang

Oct 11, 2024 | pubs.rsc.org | Yaxing Wu |Xiuling Wang |Zhenyu Wang |Chao Chen

Redox-neutral decarboxylative coupling of fluoroalkyl carboxylic acids via a dual metal photoelectrocatalysis Given the importance and beneficial characteristics of aliphatic CF3 chiral compounds in modern chemistry, efficient strategies for their synthesis are highly sought after. While α-CF3 carboxylic acid is an emerging and easily accessible CF3-containing synthon, its use as a source of fluoroalkyl is highly challenging due to its high oxidation potential.

Aug 24, 2023 | nature.com | Yaxing Wu

AbstractThe isoperfluoropropyl group (i-C3F7) is an emerging motif in pharmaceuticals, agrichemicals and functional materials. However, isoperfluoropropylated compounds remain largely underexplored, presumably due to the lack of efficient access to these compounds. Herein, we disclose the practical and efficient isoperfluoropropylation of aromatic C-H bonds through the invention of a hypervalent-iodine-based reagent-PFPI reagent, that proceeds via a Ag-X coupling process.