Yidan Xu

Aug 29, 2024 | dovepress.com | Qinghua Zhang |Lu Zhang |Yidan Xu |Guizhen Pan

Qinghua Zhang,1,* Guizhen Pan,2,* Lu Zhang,1 Yidan Xu,1 Jiqing Hao1 1Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China; 2Department of Radiation Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China *These authors contributed equally to this work Correspondence: Jiqing Hao, Department of Oncology, The First Affiliated Hospital of Anhui...

Apr 17, 2024 | dovepress.com | Yidan Xu |Lu Zhang |Zhiyang Chen |Xiaonan Sun

Back to Journals » Journal of Inflammation Research » Volume 17 Authors Xu Y , Zhang L , Chen Z , Sun X , Zhao M, Wu Q, Hao J Received 17 April 2024 Accepted for publication 14 August 2024 Published 20 August 2024 Volume 2024:17 Pages 5555—5565 DOI https://doi.org/10.2147/JIR.S474263 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Tara Strutt Yidan Xu,1,* Lu Zhang,1,* Zhiyang Chen,1 Xiaonan Sun,1 Mengdan...

Jan 2, 2024 | nature.com | Tingting Li |Yidan Xu |Qianhui Qu

AbstractThe secretion and quality control of glycosylphosphatidylinositol-anchored proteins (GPI-APs) necessitates post-attachment remodeling initiated by the evolutionarily conserved PGAP1, which deacylates the inositol in nascent GPI-APs. Impairment of PGAP1 activity leads to developmental diseases in humans and fatality and infertility in animals. Here, we present three PGAP1 structures (2.66−2.84 Å), revealing its 10-transmembrane architecture and product-enzyme interaction details.