Yikai Luo

Jan 19, 2024 | science.org | Chiho Kim |Xu-Dong Wang |Zhengshuai Liu |Jianwei Hao |Shuai Wang |Peng Li | +11 more

Aug 30, 2023 | cell.com | Yikai Luo |Computational Biosciences

Highlights Single-cell profiling technologies provide an unprecedented resolution in investigating the coordinated compositional and state alterations of immune and stromal components in response to cancer therapies on the tumor microenvironment, enabling a holistic and more nuanced understanding of treatment response and resistance.

Jul 10, 2023 | nature.com | Yikai Luo |Di Wang

AbstractAging is accompanied by homeostatic and functional dysregulation of multiple immune cell subsets. Group 3 innate lymphoid cells (ILC3s) constitute a heterogeneous cell population that plays pivotal roles in intestinal immunity. In this study, we found that ILC3s in aged mice exhibited dysregulated homeostasis and function, leading to bacterial and fungal infection susceptibility.