Ying He

Jan 9, 2025 | onlinelibrary.wiley.com | Ying He |Yan Deng |Hai Yi

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Jan 2, 2025 | nature.com | Chenyao Zhao |Nuoyi Li |Wenqing Miao |Ying He |Yandan Lin

Sleep disorders constitute a significant disruption for shift workers. Beyond medical interventions, phototherapy is recognized as an effective approach to significantly alleviate sleep disorders, particularly among individuals engaged in shift work. However, the effective dose and efficacy evaluation of phototherapy have not yet been determined. This study conducted a systematic review across five databases from January 1, 1990, to December 31, 2023. A total of 11 articles were selected for meta-analysis using a random-effects model. The results showed that light therapy significantly improved the total sleep time (TST) (MD = 32.54, p < 0.00001) and sleep efficiency (SE) (MD = 2.91, p = 0.007) of shift workers compared to the control group. Subgroup analysis and regression analysis implied that medium illuminance (900–6000 lx) for a long treatment duration (≥ 1 h) during night was more effective in extending total sleep time, whereas higher-illuminance and increasing dose (lx*h) of light therapy was more beneficial for SE. In summary, light therapy has a degree of efficacy in increasing the overall sleep duration and efficiency for shift workers, the findings of the current study contribute reference and evidence for dose setting and experimental design of phototherapy on shift workers’ sleep in clinical and research.

Aug 16, 2024 | thelancet.com | Yi Zhao |Ying He |Wei Wang |Qi Cai

1. Precision management of advanced non-small cell lung cancer. Annu Rev Med. 2020; 71: 117-1362. Midha A Dearden S McCormack R EGFR mutation incidence in non-small-cell lung cancer of adenocarcinoma histology: a systematic review and global map by ethnicity (mutMapII). Am J Cancer Res. 2015; 5: 2892-29113. NCCN clinical practice guidelines in oncology for non-small cell lung cancer. Version 2. 4. Mok TS Wu YL Thongprasert S et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma.

Apr 16, 2024 | nature.com | Ying He

AbstractThe past century has witnessed a large number of reports on the Z/E isomerization of alkenes. However, the vast majority of them are still limited to the isomerization of di- and tri-substituted alkenes. The stereospecific Z/E isomerization of tetrasubstituted alkenes remains to be an underdeveloped area, thus lacking in a stereodivergent synthesis of axially chiral alkenes.

Jan 17, 2024 | thefulcrum.us | Ying He

Beckel is the research director for Issue One, a crosspartisan political reform group. He is an intern for Issue One. More than 10,000 officials across the country run U.S. elections. This interview is part of a series highlighting the election heroes who are the faces of democracy. Wesley Wilcox, a registered Republican, has more than 32 years of experience in election administration.