Yiran Li

Feb 12, 2025 | nature.com | Xiaowen Xie |Olivia Zhang |Ceejay Lee |N. Connor Payne |Leena Paul |Yiran Li | +10 more

AbstractCancer mutations can create neomorphic protein–protein interactions to drive aberrant function1,2. As a substrate receptor of the CULLIN3-RING E3 ubiquitin ligase complex, KBTBD4 is recurrently mutated in medulloblastoma3, the most common embryonal brain tumour in children4. These mutations impart gain-of-function to KBTBD4 to induce aberrant degradation of the transcriptional corepressor CoREST5. However, their mechanism remains unresolved.

Dec 3, 2024 | nature.com | Ying Li |Yiran Li |Wei Wang |Yi Cao

AbstractWhile hydrogel-based flexible sensors find extensive applications in fields such as medicine and robotics, their performance can be hindered by the rapid evaporation of water, leading to diminished sensitivity and mechanical durability.

Oct 3, 2024 | mdpi.com | Zhongbin Sun |Xiaolong Li |Yiran Li |Yue Ma

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Sep 9, 2024 | arxiv.org | Xiaolong Li |Yiran Li |Yue Ma