Yixin Bian

Aug 19, 2024 | onlinelibrary.wiley.com | Yixin Bian |Tingting Hu |Kexin Zhao |Engineering Beijing

1 Introduction Orthopedic implants encompassing total knee/hip prosthesis, fixation instruments, and bone defect scaffolds are commonly applied in clinical practice to treat amounts bone diseases including osteoarthritis, osteonecrosis of the femoral head, fractures, critical-size bone defects, etc.[1-5] However, the implants can be frequently compromised by postoperative periprosthetic infection and prosthetic loosening, ultimately leading to prosthesis failure.[6-9] Periprosthetic infection...

Jul 3, 2024 | onlinelibrary.wiley.com | Yixin Bian |Kexin Zhao |Engineering Beijing |Tingting Hu

1 Introduction Osteosarcoma is ranked as the second leading cause of tumor-related mortality in adolescents.[1-3] Currently, limb-salvage tumor resection represents the main therapeutic strategy for osteosarcoma.[4-9] However, a dilemma arises in limb-salvage tumor resection as expanding resection scope to mitigate postoperative recurrence entails extensive bone defects, while minimizing tumor resection extent raises concerns of osteosarcoma recurrence.[10-12] Additionally, periprosthetic...