Yong S. Chu

Apr 6, 2024 | biorxiv.org | Xiao Zhang |Zihan Lin |Liguo Wang |Yong S. Chu

AbstractSegmentation of three-dimensional (3D) cellular images is fundamental for studying and understanding cell structure and function. However, 3D cellular segmentation is challenging, particularly for dense cells and tissues. This challenge arises mainly from the complex contextual information within 3D images, anisotropic properties, and the sensitivity to internal cellular structures, which often lead to miss-segmentation.