Youtao Lu

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Single-Mitochondrion Sequencing Uncovers Distinct Mutational Patterns and Heteroplasmy Landscape in Mouse Astrocytes and Neurons.

Jun 13, 2024 | biorxiv.org | Parnika S. Kadam |Zijian Yang |Youtao Lu |Hua Zhu

AbstractBackground: Mitochondrial (mt) heteroplasmy can cause adverse biological consequences when deleterious mtDNA mutations accumulate disrupting normal mt-driven processes and cellular functions.

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