Yu Teng

Aug 5, 2024 | pubs.rsc.org | Bingbing Yang |Yu Teng |Jun Ge |Xinchi Feng

Identification of α-tubulin alpha-1B chain as target of asiatic acid by chemical proteomics in HepG2 hepatoma cells Asiatic acid (AA) is a naturally occurring pentacyclic triterpene isolated from Centella asiatica and has various biological effects, most notably anticancer effects. While numerous investigations have demonstrated the possible mechanism underlying AA’s anticancer action, the precise protein target of AA remains unclear.