Yuanchang Liu

Jan 9, 2024 | pubs.rsc.org | Vincent M Rotello |Xianzhi Zhang |Yuanchang Liu |Mingdi Jiang |Javier A. Mas-Rosario

Polarization of macrophages to an anti-cancer phenotype through in situ uncaging of a TLR 7/8 agonist using bioorthogonal nanozymes Macrophages are plastic cells of the immune system that can be broadly classified as having pro-inflammatory (M1-like) or anti-inflammatory (M2-like) phenotypes. M2-like macrophages are often associated with cancers and can promote cancer growth and create an immune-suppressive tumor microenvironment.