Yueru Hou

3 weeks ago | nature.com | Zhiqiang Hu |Yueru Hou |Ying Meng |Xueli Bai |Shengzhong Duan |Xiaoguang Liu | +2 more

AbstractTumor cells adapt to the inflammatory tumor microenvironment (TME) and develop resistance to immunotherapy, with ferroptosis being a major form of tumor cell death. However, the mechanisms by which tumor cells coordinate TME stimuli and their unique metabolic traits to evade ferroptosis and develop resistance to immunotherapy remain unclear.