Yuntian Zhang

Jul 17, 2023 | biorxiv.org | Yuntian Zhang |Rachel L. Belote |Marcus Urquijo |Maike MK Hansen

New Results doi: https://doi.org/10.1101/2020.08.26.269126 AbstractHuman cancers can exhibit phenotype switching, resulting in cells that are more metastatic or that are more tolerant to treatment. However, the relationship between these aggressive states is not well understood. We investigated the dynamics of phenotypic switching in human melanoma cells by monitoring the fluorescent activity from a transgenic reporter of BRN2 promoter activation.