Zachary R McCaw

Jan 7, 2025 | mdpi.com | Jessica L. Gronsbell |Zachary R McCaw |Lu Tian |Timothy Regis

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Jun 13, 2024 | nature.com | Zachary R McCaw |Xihong Lin

AbstractWithin population biobanks, incomplete measurement of certain traits limits the power for genetic discovery. Machine learning is increasingly used to impute the missing values from the available data. However, performing genome-wide association studies (GWAS) on imputed traits can introduce spurious associations, identifying genetic variants that are not associated with the original trait.