
Zemeng Wei
Articles
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1 month ago |
biorxiv.org | Zemeng Wei |Michael Rehman |Jianlei Gu |Gabriel Lerner
AbstractThe existence of a cilia-dependent cyst activation (CDCA) pathway underlying autosomal dominant polycystic kidney disease was identified by showing that cyst progression following loss of polycystins is significantly suppressed by removal of structurally intact cilia.
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Apr 30, 2024 |
nature.com | Chao Zhang |Ke Dong |Ming Shen Tham |Zemeng Wei |Felix Behrens |Hongyu Zhao | +2 more
AbstractMouse models of autosomal dominant polycystic kidney disease (ADPKD) show that intact primary cilia are required for cyst growth following the inactivation of polycystin-1. The signaling pathways underlying this process, termed cilia-dependent cyst activation (CDCA), remain unknown.
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