Zhenqiang Sun

2 weeks ago | nature.com | Zhenqiang Sun |Yichen Zhu |Yang Liu

AbstractThe tumor-immune response is mobilized to suppress tumorigenesis, while the immune microenvironment and lymph node microenvironment are formed gradually during tumor progression. In fact, tumor surface antigens are not easily recognized by antigen-presenting cells. So it is hard for the immune system to kill the newly formed tumor cells effectively.

Sep 27, 2024 | nature.com | Zhenqiang Sun |Wenkang Wang |Yang Liu

AbstractTumor progression of colorectal cancer (CRC) seriously affects patient prognosis. For CRC patients with advanced-stage disease, it is still necessary to continuously explore more effective targeted therapeutic drugs. Circular RNAs (circRNAs) are involved in the regulation of tumor biology. We screened circAURKA, which was significantly highly expressed in CRC by previous high-throughput RNA sequencing.

Jan 19, 2024 | nature.com | Wenkang Wang |Wendong Wang |Zhenqiang Sun

AbstractAs the latest and most anticipated method of tumor immunotherapy, CAR-NK therapy has received increasing attention in recent years, and its safety and high efficiency have irreplaceable advantages over CAR-T. Current research focuses on the application of CAR-NK in hematological tumors, while there are fewer studies on solid tumor.

Jul 28, 2023 | nature.com | Zhenqiang Sun

Retraction to: Oncogene https://doi.org/10.1038/s41388-018-0628-y, published online 10 December 2018The Editors-in-Chief have retracted this article after publication irregularities were spotted in the following figures:In figure 1H there is overlap between the image of pEGFP-c1-YAP1 invasion image and the pEGFP-c1-YAP1 migration image. In figure 4A at 0h the control image and the YAP1 image are identical.

Mar 15, 2023 | nature.com | Zhenqiang Sun

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