Zhichao Jiang

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The canonical single-stranded DNA binding protein SSB is not an essential replication protein but an RNA chaperon in the hyperthermophilic archaeon Saccharolobus islandicus REY15A

Jul 7, 2023 | biorxiv.org | Yuanxi Xiao |Zhichao Jiang |Mengqi Zhang |Xuemei Zhang

New Results doi: https://doi.org/10.1101/2023.07.06.548054 AbstractSingle-stranded DNA binding proteins (SSBs) have been regarded as indispensable factors in all three domains of life since they play vital roles in DNA replication. Herein, we report that genes coding for the canonical SSB (SisSSB) and the non-canonical SSB (SisDBP) in the hyperthermophilic archaeon Saccharolobus islandicus REY15A can both be deleted.

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