Zhiqun Zhao

Oct 28, 2024 | onlinelibrary.wiley.com | Guangyu Ji |Jia Liu |Zhiqun Zhao |Jie Lan

Graphical Abstract Breast Cancer Stem Cells Article number 2404853 by Kai Zhang, Qi Mei, Rong Sun, Haiquan Lu, and co-workers reveals the critical role of polyamine anabolism in chemotherapy-induced breast cancer stem cell (BCSC) enrichment.

Jul 26, 2024 | onlinelibrary.wiley.com | Jia Liu |Jie Lan |Guangyu Ji |Zhiqun Zhao

1 Introduction Cytotoxic chemotherapy is a widely-used systemic treatment for early-stage and advanced breast cancer patients.[1, 2] Although many patients initially respond to chemotherapy, they often experience tumor recurrence and metastasis.[3] The existence of breast cancer stem cells (BCSCs), a small subpopulation of breast cancer cells that possess infinite proliferative potential and tumor-initiating capacity, is the major reason for chemoresistance and tumor relapse.[4-8] Recent...