Zhiyi Pan

Oct 31, 2024 | mdpi.com | Tao Song |Haonan Song |Zhiyi Pan |Yuan Gao

1. IntroductionDefining transcriptional regulatory signals is crucial for understanding eukaryotic gene expression [1]. In bioinformatics, enhancers and super-enhancers are positive regulators of gene transcription [2]. There is substantial evidence that enhancer-based transcriptional regulation is involved in determining cell fate and tissue development [3,4,5].