Zhou H Tiffany

1 month ago | biorxiv.org | Xue Li |Allison Cohen |Zhou H Tiffany

AbstractThe relationship between parasite genotype and pathogenesis is largely unknown for Cryptosporidium, a leading cause of diarrheal disease in children. An array of parasites with similar genomes produces varied disease outcomes in different hosts. Here, we isolate and characterize Cryptosporidium parvum strains that show marked differences in virulence and persistence in mice.