Zhu Liu

Jan 2, 2025 | nature.com | Zhu Liu

AbstractXPR1 is the sole protein known to transport inorganic phosphate (Pi) out of cells, a function conserved across species from yeast to mammals. Human XPR1 variants lead to cerebral calcium-phosphate deposition and primary familial brain calcification (PFBC), a hereditary neurodegenerative disorder. Here, we present the cryo-EM structure of human XPR1 in both its Pi-unbound and various Pi-bound states.

Aug 20, 2024 | biorxiv.org | Zhu Liu |Huazhong Agricultural

AbstractXPR1 is the only known protein responsible for transporting inorganic phosphate (Pi) out of cells, a function conserved from yeast to mammals. Human XPR1 variants lead to cerebral calcium-phosphate deposition, which are associated with a hereditary neurodegenerative disorder known as primary familial brain calcification (PFBC). Here, we present the cryo-EM structure of human XPR1 in both its Pi-unbound form and various Pi-bound states.

Dec 12, 2023 | nature.com | Wenli Zhao |Biqing Zhu |Steven J. Davis |Philippe Ciais |Chaopeng Hong |Zhu Liu

AbstractIncreasing extreme climate events driven by climate change raise the question of their impacts on the power production system, and implications for renewable versus fossil power supply. Here, using climate reanalysis data and daily electricity generation (2018–2023), we systematically quantify the impact of extreme climate events, specifically extreme cold events and extreme hot events on United States state-level carbon emissions and on the carbon intensity of electricity.

Jun 15, 2023 | rmets.onlinelibrary.wiley.com | Zhu Liu

Köppen–Geiger climate zones were originally constructed to designate the manifold climates to reflect the mean spatial climate characteristics, which includes the Tropical Zone, Dry Zone, Temperate Zone, Continental Zone and Polar Zone. In this study, 20 CMIP6 models are applied to evaluate historical net radiation (R ) climatology during 1950–2014 for the five Köppen–Geiger climate zones, respectively.