Zia Moinuddin

Apr 13, 2024 | anaesthesiajournal.co.uk | Jennifer Kingston |Shiraz Khan |Zia Moinuddin

The nephron is the functional unit of the kidney involved in the critical interplay of fluid and electrolyte homeostasis by glomerular filtration, selective tubular reabsorption, and secretion. This article will discuss the structure and function of each segment of the nephron, and the physiology pertaining to the formation of urine.

Apr 6, 2024 | anaesthesiajournal.co.uk | Shiraz Khan |Jennifer Kingston |Zia Moinuddin

The homeostatic and excretory functions of the kidney are dependent on its perfusion, totalling 20–25% of cardiac output, and the process of glomerular ultrafiltration. Renal blood flow (RBF) is directly proportional to the trans-renal gradient which is autoregulated across a mean arterial pressure of 50–150 mmHg in a normotensive person.