Zixuan Li

Jun 3, 2024 | biorxiv.org | Brittany Carr |Dominic Skitsko |Jun Song |Zixuan Li

AbstractMutations in the PROMININ-1 (PROM1) gene are associated with inherited, non-syndromic vision loss. Here, we used CRISPR/Cas9 to induce truncating prom1-null mutations in Xenopus laevis to create a disease model. We then tracked progression of retinal degeneration in these animals from the ages of 6 weeks to 3 years old.

Jul 4, 2023 | mdpi.com | Jiawei Xue |Yanhong Li |Zixuan Li |Yue Cui

4. ExperimentIn this section, we introduce the in-domain and out-of-domain datasets, the experimental setting and the study of hyper-parameters, the baseline methods, the experimental results and analysis, the ablation study, and the case study.