EMJ- European Medical Journal

The European Medical Journal is a specialized publisher that merges expert editorials from influential figures with brief news summaries from major industry congresses. This approach provides top-notch insights into the latest developments and progress in both clinical and pharmaceutical fields.

International

English

Journal

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Ranking

Global

#398680

United Kingdom

#66233

Health/Medicine

#265

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Articles

Prostate Cancer Surgery Rates Drop in Low-Risk Cases

1 week ago | emjreviews.com | Katie Wright

A LARGE retrospective cohort study has revealed a significant decline in the surgical overtreatment of low-risk prostate cancer over the past two decades. By analysing data from 185,928 male patients across two registries, Surveillance, Epidemiology, and End Results (SEER) and the Michigan Urological Surgery Improvement Collaborative (MUSIC), researchers found a more than fivefold reduction in the number of prostatectomies resulting in pathologic grade group 1 (pGG1) diagnoses from 2010 to 2024.
Blood Test Reveals Early Biomarkers for Teen Depression

1 week ago | emjreviews.com | Katie Wright

A BLOOD test identifying nine specific microRNAs has been found to distinguish adolescents with depression from their healthy peers, offering a promising new biomarker for early detection and intervention in teenage depression. Adolescent depression is a growing public health concern, often leading to chronic symptoms, poor treatment response, and lifelong mental health challenges.
Flu Vaccine Prevented Over 100,000 Hospitalisations Last Winter

1 week ago | emjreviews.com | Katie Wright

FLU vaccination prevented up to 120,000 hospital admissions in England during the 2024/25 season, despite concerning declines in uptake among some vulnerable groups, UK Health Security Agency (UKHSA) reports. The UKHSA analysed national flu data for the 2024/25 winter season, marked by high influenza activity and pressure on NHS services. Using routine surveillance and vaccine effectiveness modelling, the agency estimated that the flu vaccine averted between 96,000 and 120,200 hospitalisations.
Autism in Toddlers: No Early Sex Differences at First Diagnosis

1 week ago | emjreviews.com | Katie Wright

A LARGE-SCALE study of over 2,500 toddlers has found no significant early-age clinical differences between males and females with autism spectrum disorder (ASD), suggesting that sex differences in autistic traits may emerge later in development rather than at the time of first diagnosis. Understanding whether boys and girls with autism present with different symptoms at the earliest stages of life is crucial for early identification, intervention, and tailoring support.
Tezepelumab Achieves Clinical Remission in Severe Asthma

1 week ago | emjreviews.com | Katie Wright

SEVERE ASTHMA is a complex and burdensome condition, often resistant to conventional therapies. Biologics targeting type 2 (T2) inflammation have transformed treatment, improving symptoms and reducing exacerbations. Tezepelumab, a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), offers broader T2 suppression and is unique in being licensed for use regardless of T2 biomarker levels.
Combination Therapy Improves Outcomes in Prostate Cancer

2 weeks ago | emjreviews.com | Katrina Thornber

ENZALUTAMIDE, an oral androgen receptor inhibitor, has demonstrated significant clinical benefit in men with metastatic hormone-sensitive prostate cancer (mHSPC), particularly when used in combination with androgen deprivation therapy (ADT). Findings from the pivotal ARCHES trial revealed that enzalutamide plus ADT significantly improved radiographic progression-free survival (rPFS) and overall survival (OS) compared to placebo plus ADT.
Brensocatib Reduces Exacerbations in Patients with Bronchiectasis

2 weeks ago | emjreviews.com | Katrina Thornber

A ONCE-daily oral therapy targeting neutrophilic inflammation has shown promise in reducing exacerbations in patients with bronchiectasis, according to results from a large Phase 3 trial. The double-blind, randomised study enrolled 1,721 patients, including 1,680 adults and 41 adolescents, and allocated them to receive either 10 mg or 25 mg of brensocatib, or placebo.
EuroPCR 2025: 10-year Results of the DANAMI-3-PRIMULTI Trial

2 weeks ago | emjreviews.com | Katrina Thornber

FFR-guided complete revascularisation reduces long-term repeat cardiovascular events compared with infarct-related artery only treatment in patients with STEMI and multivessel disease, according to the 10-year results of the DANAMI-3-PRIMULTI trial presented at EuroPCR 2025. The optimal long-term strategy for managing patients presenting with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease remains a subject of ongoing debate.
Seasonal Allergy Symptoms Improved With New Biologic Treatment

2 weeks ago | emjreviews.com | Katrina Thornber

SEASONAL allergic rhinitis (SAR), a common yet often debilitating condition, is triggered by airborne allergens and marked by intense nasal inflammation. Unlike perennial allergic rhinitis (PAR), SAR presents more severe symptoms and has proven more difficult to manage, especially as climate change threatens to exacerbate pollen levels and extend allergy seasons.
AI Model Enhances Liver Cancer Risk Prediction Accuracy

2 weeks ago | emjreviews.com | Katie Wright

A NOVEL AI model named PLAN-B-DF has been developed to improve the prediction of hepatocellular carcinoma (HCC) risk in patients with chronic hepatitis B (CHB). Unlike previous models, which relied primarily on clinical and demographic data, PLAN-B-DF incorporates imaging biomarkers derived from abdominal CT scans using a deep learning-based auto-segmentation algorithm called DeepFore.