Environmental Health Perspectives

Environmental Health Perspectives (EHP) is a monthly peer-reviewed journal backed by the U.S. National Institute of Environmental Health Sciences (NIEHS). Its main goals are to share the latest research and developments in the field of environmental health, enhance the understanding of environmental health among researchers, policymakers, and administrators, and educate the public on significant issues related to environmental health. In 2015, EHP achieved an impact factor of 8.44.

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Assessing the potential impacts of California Senate Bill 27 (SB27) on the antimicrobial susceptibility of Escherichia coli from raw meat

2 weeks ago | ehp.niehs.nih.gov | Lance B. Price

Formats available You can view the full content in the following formats: Supplementary Material File (ehp16115.s002.acco.zip) File (ehp16115.smcontents.508.pdf) File (ehp16115.s001.acco.pdf) Information & Authors Published In Environmental Health Perspectives History Received: 27 August 2024 Revision received: 23 April 2025 Accepted: 19 May 2025 Published online: 11 June 2025 Notes Conclusions and opinions are those of the individual authors and do not necessarily reflect the policies or...
Valley Fever: Fine Mineral Dust Modeling Points to High-Risk Regions and Seasons in California

Jan 21, 2025 | ehp.niehs.nih.gov | Silke Schmidt

An increasing incidence of fungal diseases is a lesser-known consequence of climate change.1 A case in point is Valley fever, caused by inhaling spores of the Coccidioides fungus, which grows in the soil.2 One pathogenic Coccidioides species is commonly found in Arizona and another in California’s San Joaquin Valley, Central Coast, and southern deserts.2 Valley fever cases in California have tripled since 2014,3 and the extent to which the fungus has spread to other parts of the United States...
Estimating the Exposure-Response Relationship between Fine Mineral Dust Concentration and Coccidioidomycosis Incidence Using Speciated Particulate Matter Data: A Longitudinal Surveillance Study | Environmental Health Perspectives | Vol. 133, No. 1

Jan 13, 2025 | ehp.niehs.nih.gov | Justin V Remais

IntroductionCoccidioidomycosis is an emerging infectious disease with the highest burden of disease in the southwestern US. Recent decades have seen a more than 8-fold increase (2.4 to 18.8 cases/100,000 population) in age-adjusted incidence in California between 2000 and 2018.1 Infection occurs following the inhalation of the fungal arthroconidia (2–4μm)2 of the genus Coccidioides, including C. immitis, most prevalent in California, and C. posadasii, most prevalent in Arizona.3,4 C.
When It Rains It Pours: Campylobacter Infection Rates after Rain on Wet and Dry Soils

Jan 13, 2025 | ehp.niehs.nih.gov | Charles Schmidt

Campylobacter jejuni affects nearly 550 million people worldwide, many of them young children, with diarrheal illness; it is among the top four causes of diarrheal disease worldwide.1–3 This microbe naturally inhabits the intestines of wild birds, poultry, cattle, swine, and other animals.1 Human exposures typically occur when people ingest contaminated food or water,1 or work in settings such as poultry farms and slaughterhouses.4,5 Climatic factors are associated with changes in...
Association of Postpartum Temperature Exposure with Postpartum Depression: A Retrospective Cohort Study in Southern California

Nov 27, 2024 | ehp.niehs.nih.gov | Darios Getahun |Jun Wu

Introduction As the perinatal form of major depressive disorder, postpartum depression (PPD) is one of the most frequent childbirth complications.1 Postpartum depressive symptoms affect ∼10%–20% of new mothers worldwide.1–4 Mothers with PPD experience symptoms, such as feelings of anhedonia, worthlessness or guilt, depressed mood, insomnia, or hypersomnia, that can last for up to 1 y postpartum, and infants born to mothers with PPD are at a greater risk of developing behavioral and emotional...
Diversity under a Microscope: As Biodiversity Diminishes, Do Allergies and Asthma Increase?

Nov 21, 2024 | ehp.niehs.nih.gov | Kelley Christensen

Our planet may be experiencing its sixth known mass extinction event,1,2 with a precipitous loss of insects,3 birds,4 and other species.5 Unseen by our eyes, even Earth’s microbial biodiversity is decreasing.6,7 Yet human immune systems rely on microbial exposures to build up defenses.8,9 In a state-of-the-science review published recently in Environmental Health Perspectives,10 researchers assessed studies on the relationships between the inner and outer layers of microbial...
Organophosphorus Flame Retardants and Metabolic Disruption: An in Silico, in Vitro, and in Vivo Study Focusing on Adiponectin Receptors

Nov 8, 2024 | ehp.niehs.nih.gov | Ying Liu |Xiaochun Ma |Yifei Le |Jiafan Feng

Introduction Anthropogenic compounds, particularly endocrine disruption chemicals (EDCs), are being recognized for their unprecedented impact on the increasing worldwide prevalence of metabolic syndromes,1 and the mechanisms underlying EDC-associated metabolic disruption are being investigated as matters of global significance.2 The potential modes of action of EDC-elicited metabolic disruption have been well studied in relation to nuclear receptors,1 which are broad targets for EDCs. Indeed,...
Madagascar’s Plague: One Health Research Aims to Slow Its Spread

Nov 7, 2024 | ehp.niehs.nih.gov | Wendee Nicole

: Environmental Health PerspectivesVolume 132, Issue 11CID: 112001Clad in a cobalt blue jumpsuit—the field outfit of the Pasteur Institute of Madagascar (IPM)—Malagasy scientist Adélaïde Miarinjara was tweezing fleas, one by one, from a plate of soapy water, a “candle trap” she had set the night before inside a family home. Like others in the region, the two-story house arises from the rust-red earth it is made from, topped with a palm-thatch roof.
Gut Check: Microbiota and Obesity in Mice Exposed to Polystyrene Microspheres

Nov 3, 2024 | ehp.niehs.nih.gov | Wendee Nicole

Intestinal microbes are known to regulate certain aspects of metabolism in mice1,2 and humans.3 Microplastics are one environmental exposure that can disrupt the balance of gut microbiota in mouse models.4,5 Generally defined as plastic particles measuring 1μm to 5mm in diameter,6 microplastics have been documented in various human body tissues and excreta,7 leading to a growing interest in how exposures may affect human health outcomes.8 In a study recently published in Environmental Health...
A Bigger Big Picture: Insights on Environmental Chemicals and Dyslipidemia through Combined “Omic” Analyses

Oct 25, 2024 | ehp.niehs.nih.gov | Charles Schmidt

Cardiovascular disease (CVD) kills millions of people globally every year.1 Environmental pollutants are increasingly recognized as significant risk factors for these conditions,2,3 but the underlying biological mechanisms are poorly understood.4 New research reported in Environmental Health Perspectives may provide needed insights.5 The findings come from the ongoing Biomarkers of Air Pollutant Exposure (BAPE) study, conducted by scientists at the Chinese Center for Disease Control and...