European Urology

1 month ago | europeanurology.com | Alberto Briganti |Vita-Salute San Raffaele |Jason A. Efstathiou |Ribeirão Preto

aDepartment of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, Rome, Italy bUnit of Urology/Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy cDepartment of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA dDepartment of Radiology, Heersink School of Medicine, University of Alabama, Birmingham, AL, USA eDepartment of Radiology, Columbia...

1 month ago | europeanurology.com | Juan Rivas

Saad F, Vjaters E, Shore N, et alJ Clin Oncol 2024;42:4271–81Experts’ summary:The ARANOTE trial assessed the efficacy and safety of darolutamide in combination with androgen deprivation therapy (ADT) in comparison to ADT alone in patients with metastatic hormone-sensitive prostate cancer (mHSPC). In this double-blind, phase 3 trial, 669 patients were randomized in a 2:1 ratio.

1 month ago | europeanurology.com | Juan Rivas |Jesús Sierra

Emmett L, Subramaniam S, Crumbaker M, et alLancet Oncol 2024;25:563–71Experts’ summary:The ENZA-p trial assessed the efficacy and safety of combining [177Lu]Lu-PSMA-617 with enzalutamide in comparison to enzalutamide alone in patients with metastatic castration-resistant prostate cancer (mCRPC) and at least two risk factors for early progression. This open-label, randomized, phase 2 trial enrolled 162 patients across 15 centers in Australia.

2 months ago | europeanurology.com | Matthew J. Roberts

1 Why perform pelvic lymph node dissection? Pelvic lymph node dissection (PLND) performed during radical prostatectomy (RP) has been recommended for many years by international guidelines, including previous editions of the EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines, for staging purposes and a potential oncological benefit. An extended PLND (ePLND) template detects more metastases than a standard template and so is recommended by the guidelines when PLND is deemed necessary.

2 months ago | europeanurology.com | Albert Carrion |Richard Cathomas |Eva M. Compérat |Konstantinos Dimitropoulos |Jason A. Efstathiou |Rainer Fietkau | +6 more