Memorial Sloan Kettering Cancer Center

1 week ago | mskcc.org | Julie Grisham

Researchers from Memorial Sloan Kettering Cancer Center (MSK) reported important advances in the treatment of lung cancer at the annual meeting of the American Society of Clinical Oncology (ASCO), held May 30 to June 3 in Chicago. Scientists presented promising results on three different targeted therapies — one for small cell lung cancer and two for non-small cell lung cancer.

3 weeks ago | mskcc.org | Julie Grisham

Memorial Sloan Kettering Cancer Center (MSK) celebrated new graduates and award winners at the Academic Convocation and Commencement, held on May 14. In 2025, 14 students earned their doctoral degrees in cancer biology from the Gerstner Sloan Kettering Graduate School of Biomedical Sciences (GSK) — the educational division of MSK. In addition, two practicing MSK doctors received Master of Science degrees in clinical and translational cancer research from GSK.

3 weeks ago | mskcc.org | Julie Grisham

The first drug for a rare and difficult-to-treat type of ovarian cancer has been granted accelerated approval by the Food and Drug Administration (FDA). The treatment, called avutometinib plus defactinib (Avmapki Fakzynja Co-pack), was developed to treat low-grade serous ovarian cancer (LGSOC). The phase 2 clinical trial that resulted in the approval was led in the United States by gynecologic medical oncologist Rachel Grisham, MD, of Memorial Sloan Kettering Cancer Center (MSK).

1 month ago | mskcc.org | Julie Grisham

I conducted my dissertation research in the laboratory of John Maciejowski, PhD, whose work centers on cytosolic DNA sensing and innate immune signaling in chromosomally unstable cancers. These cancers frequently exhibit mitotic errors, leading to the formation of micronuclei — small, aberrant nuclear structures that encapsulate mis-segregated chromosomes or chromosomal fragments. Due to their fragile nuclear envelopes, micronuclei are prone to spontaneous rupture, exposing DNA to the cytosol.

1 month ago | mskcc.org | Julie Grisham

Doctors and scientists have known for nearly a decade that a precancerous blood condition called clonal hematopoiesis (CH) is present in one in three patients with solid tumors and is associated with poor cancer outcomes. People with CH are less likely to respond to treatment and are more likely to develop a secondary leukemia related to chemotherapy.