NeurologyLive
NeurologyLive™ provides both print and digital media resources tailored for healthcare professionals focused on treating neurological disorders. It delivers vital news and insights straight from leading medical conferences and experts in the field. This platform offers a comprehensive overview of the numerous new treatments being developed, showcasing their innovative mechanisms of action. As the need for neurology specialists continues to rise, NeurologyLive™ keeps its audience informed with the latest clinical trial outcomes, FDA approvals, groundbreaking research, and expert opinions.
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Articles
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5 days ago |
neurologylive.com | Marco Meglio
Using more than 250,000 person years (PYs) of exposure data, results from a recent analysis showed that the safety profile of cladribine (Mavenclad; EMD Serono), an FDA-approved medication for multiple sclerosis (MS), was consistent with findings from its clinical development program and previous safety updates.
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5 days ago |
neurologylive.com | Marco Meglio
Newly reported data from the phase 3 OPTIMUM-LT open-label extension trial (NCT03232073) showed that treatment with ponesimod (Ponvory; Vanda Pharmaceuticals) was safe and led to sustained reduction in relapses, MRI lesions, and low disability accumulation among patients with relapsing multiple sclerosis over a long-term period.
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5 days ago |
neurologylive.com | Marco Meglio
In a survey of Members of the Medical Partnership 4 MS+ (MP4MS+), a group of more than 1300 neurologists, a large majority of respondents agreed that disability, age, and ambulation should not preclude disease-modifying therapy (DMT) use in older patients with multiple sclerosis (MS). Overall, most neurologist felt that individualized assessment, rather than age-based rules, should be applied when considering DMT discontinuation following long-term stability.
BTK Inhibitor Fenebrutinib Demonstrates Long-Term Suppression of MS Activity in Open-Label Extension
5 days ago |
neurologylive.com | Marco Meglio
Newly presented results from the open-label extension (OLE) of the phase 2 FENopta study (NCT05119569) showed that patients with relapsing multiple sclerosis (RMS) on fenebrutinib (Genentech) had low relapse rates with no active brain lesions or disability progression after 2 years of treatment.
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6 days ago |
neurologylive.com | Marco Meglio
Findings from a non-interventional primary data collection study of adults with multiple sclerosis (MS) showed that significantly higher patients on ocrelizumab (Ocrevus; Genentech) experienced wearing off related symptom worsening while on medication than those prescribed ofatumumab (Kesimpta; Novartis).1The real-world study comprised 75 patients treated with ofatumumab for at least 6 months and 60 on ocrelizumab for at least 1 year.
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