Contagion Live

Contagion® serves as a comprehensive news platform dedicated to all aspects of infectious diseases. Our offerings include a website, a quarterly journal, email newsletters, social media updates, and the Outbreak Monitor. These resources deliver targeted information to healthcare professionals and specialists, aimed at enhancing patient care and aiding in the identification, diagnosis, treatment, and prevention of infectious diseases. Our goal is to empower both the healthcare community and the public with valuable knowledge, enabling better decision-making that positively influences patient outcomes.

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Discovery of PfAnchor Reveals New Vulnerability in Malaria Parasite’s Survival Mechanism

1 week ago | contagionlive.com | Sophia Abene

April 17, 2025Sabrina Absalon, PhD's research uncovers the essential role of PfAnchor in apicoplast division, opening avenues for targeted antimalarial therapies. A newly characterized protein, dubbed PfAnchor, is essential for the division and inheritance of a vital organelle in Plasmodium falciparum, the deadliest malaria parasite. The discovery, published as a preprint on bioRxiv, could open the door to novel antimalarial strategies targeting parasite-specific processes.
Disrupting HBV Chromatin Structure Blocks X Gene Transcription and Infection

1 week ago | contagionlive.com | Sophia Abene

Hepatitis B virus (HBV) relies on a unique DNA structure called cccDNA to initiate infection. This viral DNA forms a minichromosome by associating with host histone proteins, but the role of this structure in regulating viral gene expression has been unclear.
CDC ACIP Meeting Examines Next Steps for Meningococcal, RSV, and Chikungunya Vaccination

1 week ago | contagionlive.com | Sophia Abene

Today, April 16, 2025, the Advisory Committee on Immunization Practices (ACIP) met to review and vote on vaccine recommendations. The discussions covered meningococcal vaccines, the RSV vaccine for adults, and the chikungunya vaccine for travelers and at-risk individuals. Meningococcal VaccineThe ACIP recommends that GSK’s MenABCWY vaccine may be used when both MenACWY and MenB vaccines are indicated at the same visit.
Pennsylvania Added to the List of States With Measles Outbreaks

1 week ago | contagionlive.com | John Parkinson

This week, Pennsylvania has been added to the list of states with a measles outbreak. Two more cases were diagnosed recently in Erie County, Pa which is in the western part of the state. There have been 5 confirmed cases reported in this county since late March.
Gene Editing Therapy Receives FDA Fast Track Status in Aiming For Potential Chronic HBV Cure

1 week ago | contagionlive.com | John Parkinson

April 16, 2025Precision BioSciences received the designation for its gene editing therapy, PBGENE-HBV, developed to eliminate the root cause of chronic hepatitis B virus (HBV). The FDA granted a fast track designation to clinical stage gene editing company, Precision BioSciences, for its investigational gene therapy, PBGENE-HBV.
Over 3 Million Children Died from AMR Linked Infections in 2022

1 week ago | contagionlive.com | Sophia Abene

Research presented at this year’s ESCMID Global Congress 2025 highlights a steep and deadly rise in pediatric AMR cases, particularly in Southeast Asia and Africa, which together accounted for more than 1.4 million of the total deaths. Most of these fatalities were linked to the use of Watch and Reserve antibiotics, which are typically intended for limited use due to their high potential to drive resistance.
Newly FDA Approved UTI Antibiotic Shows High Efficacy for Gonorrhea Treatment

1 week ago | contagionlive.com | John Parkinson

Gepotidacin, which was FDA approved last month for uncomplicated urinary tract infections, was found to be efficacious against gonorrhea even slightly exceeding the standard treatment for the sexually transmitted infection (STI). The study’s results were published in The Lancet.
Updated H5N1 Report: 70 Human Cases in the US as of April 2025

1 week ago | contagionlive.com | Sophia Abene

As of April 2025, the CDC has reported 70 confirmed and probable human cases of H5N1 avian influenza since the outbreak began in 2024 in the United States. The majority of these cases have been linked to exposure through commercial agricultural settings, with 41 individuals exposed through infected dairy herds and 24 associated with poultry farms and culling operations.
Impact of CDC Hepatitis Lab Closure on US Public Health

1 week ago | contagionlive.com | Sophia Abene

On April 1, 2025, the closure of the CDC's hepatitis laboratory significantly affected the United States' ability to manage hepatitis outbreaks and prevent further transmission of viral hepatitis. The lab, part of the National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention, was essential for testing, surveillance, and monitoring hepatitis viruses, including hepatitis B (HBV) and hepatitis C (HCV).
Longhorn Advances a Scalable Universal Flu Vaccine

1 week ago | contagionlive.com | Sophia Abene

Longhorn Vaccines and Diagnostics has introduced a novel single-composite peptide vaccine that offers broad protection against human, avian, and swine influenza strains including pandemic variants such as H5N1. The unconjugated vaccine combines highly conserved epitopes from key influenza proteins, hemagglutinin (HA), neuraminidase (NA), and matrix proteins (M1, M2, M2e)—with the ALFQ adjuvant to stimulate a strong immune response.